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   Technology and Product Development

    Basic Information

Technology developed: CIRC- ASSAY for detecting A1, A2, Beta casein milk in cattle and buffalo (TP19762602070)
Category: Technology Service/Know how
Details of Inventor(s):
Inventor Institution/Organization/Company Department Designation
Indrajit Ganguly ICAR- Central Institute for Research on Cattle Cattle Genetics and Breeding Principal Scientist
Umesh Singh ICAR- Central Institute for Research on Cattle Cattle Genetics and Breeding Principal Scientist
G K Gaur ICAR- Central Institute for Research on Cattle Cattle Genetics and Breeding Principal Scientist
Sushil Kumar ICAR- Central Institute for Research on Cattle Cattle Genetics and Breeding Principal Scientist
Rani Alex ICAR- Central Institute for Research on Cattle Cattle Genetics and Breeding Scientist
Rajib Deb ICAR- Central Institute for Research on Cattle Cattle Genetics and Breeding Scientist
Sunil Kumar ICAR- Central Institute for Research on Cattle Cattle Genetics and Breeding SRF
Sandeep Mann ICAR- Central Institute for Research on Cattle Cattle Genetics and Breeding RA
Technical Application Area: Agricultural
If 'Other', please specify:
Please give more details of new technical application area:
Organization(s):
ICAR Central Institute for Research on Cattle (CIRC) Meerut
Affiliated Ministry: Institution Funding (Self Supported)
Type of technology development: Indigenous
Does the technology help in replacing any import items currently
procured from outside India?
Does the technology have export potential? 1
Category of Technology developed: Futuristic
Stage of Development: Lab-scale
Please describe in detail including the TRL Level:
The CIRC- assay for detecting A1A2 milk in cattle and buffalo has been developed and validated for routine screening of blood and milk samples obtained from different breeds of cattle and buffalo for identifying A1, A2 milk. The samples received from outside institutes, NGO and Progressive farmers are being screened for A1 and A2 milk using this technology. The technology is at the level of TRL- 5. The technology has been submitted to the Agrinnovate India Limited to find potential buyer

    Abstract:

Applications: Genetic test developed and available for detection of A1, A2, Beta casein milk. AS-PCR based technique has been developed to identify the genotype of individual animal for beta casein gene variants which has been associated with a number of human diseases.
Advantages: This technology helps for identifying animals with A2 alleles in the cattle populations. Consuming A2 milk is suggested to be beneficial for the health while A1 milk is supposed to increase certain diseases. NOVEL FEATURES Rapidity - as the test can be completed in 5 to 6 hours User friendliness - as it is easy to perform and a one step process Economical - because it does not need expensive reagents (such as real time PCR machine, restriction enzyme, reagents for PAGE, Staining solution etc.) Specificity - as the assay employs a multi set of primers with deliberately incorporated mutation

    Technology Inputs:

Imported Equipment/Spare Parts:
Equipment/Spare Parts Year ITC-HS Code
NA
Indigenous Equipment/Spare Parts:
Equipment/Spare Parts Year ITC-HS Code
NA
Imported Raw Materials:
Raw Materials Year ITC-HS Code
NA
Indigenous Raw Materials:
Raw Materials Year ITC-HS Code
NA
Existing R&D Facilities used:
Facilities Year ITC-HS Code
NA

   Patents & Publications:

Patents:
Filed Patents (No.) Granted Patents (No.) Year
0 0 NA
Publications:
Submitted (No.) Published (No.) Year
0 1 2013-14

    Commercialization Potential:

Who are the Potential Licensees?
What commercially available products address
the same problem?
Company Product Problem Addressed
Would you like to develop this invention further with
corporate research support?
Yes
Would you be interested in participating in cluster based
programs for commercialization research or business
planning for your invention?
Yes
      Submitted by: The Director Date of Submission: 7-8-2020



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