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  Digital Catalogue for Technology and Products Development


   Technology and Product Development

    Basic Information

Technology developed: Role of SPINK1 in cancer progression: Regulatory Mechanisms and Therapeutic Target Potential (TP19762829032)
Category: Product(Hardware/Material/Software)
Details of Inventor(s):
Inventor Institution/Organization/Company Department Designation
Prof. Bushra Ateeq Indian Institute of Technology (IIT) Kanpur
Technical Application Area: Chemicals & Materials Science
If 'Other', please specify:
Please give more details of new technical application area:
Organization(s):
Indian Institute of Technology (IIT) Kanpur
Affiliated Ministry: Institution Funding (Self Supported)
Type of technology development: Indigenous
Does the technology help in replacing any import items currently
procured from outside India?
Yes
Does the technology have export potential? Yes
Category of Technology developed: Immediate Deployment
Stage of Development: Prototype Level
Please describe in detail including the TRL Level:
READY

    Abstract:

Applications: The prevalence of SPINK1 outlier expression or ETS genetic rearrangement status among prostate cancer PCa patients is largely unknown in India. This project proposes to characterize the full spectrum of the PCa specific driver aberrations in a large cohort of Indian prostate cancer specimens, with specific focus on estimating the prevalence of SPINK1 over expression.
Advantages: Therefore, this study, a first of its kind, will provide a thorough understanding of causal genomic events of PCa in the Indian population. Furthermore, this will also unravel the underlying mechanism for the increased SPINK1 expression in a subset of aggressive Pca and its role in cancer metastases. This comprehensive study will also explore the potential of SPINK1 to serve as a therapeutic target in SPINK1 PCa patients.

    Technology Inputs:

Imported Equipment/Spare Parts:
Equipment/Spare Parts Year ITC-HS Code
NA
Indigenous Equipment/Spare Parts:
Equipment/Spare Parts Year ITC-HS Code
NA
Imported Raw Materials:
Raw Materials Year ITC-HS Code
NA
Indigenous Raw Materials:
Raw Materials Year ITC-HS Code
NA
Existing R&D Facilities used:
Facilities Year ITC-HS Code
NA

   Patents & Publications:

Patents:
Filed Patents (No.) Granted Patents (No.) Year
0 0 NA
Publications:
Submitted (No.) Published (No.) Year
0 0 NA

    Commercialization Potential:

Who are the Potential Licensees?
What commercially available products address
the same problem?
Company Product Problem Addressed
Would you like to develop this invention further with
corporate research support?
Yes
Would you be interested in participating in cluster based
programs for commercialization research or business
planning for your invention?
Yes
      Submitted by: Technical Team Date of Submission: 1-5-2023



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