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  Digital Catalogue for Technology and Products Development


   Technology and Product Development

    Basic Information

Technology developed: Process for producing warfarin or 3-SUBSTITUTED 4-HYDROXYCOUMARIN (TP19762895677)
Category: Technology Service/Know how
Details of Inventor(s):
Inventor Institution/Organization/Company Department Designation
Mohammad Ali Haider Indian Institute of Technology Delhi Chemical Engineering, Renewable Energy and Chemica Associate Professor
Technical Application Area: Healthcare
If 'Other', please specify:
Please give more details of new technical application area:
Organization(s):
Indian Institute of Technology (IIT) Delhi
Affiliated Ministry: Institution Funding (Self Supported)
Type of technology development: Indigenous
Does the technology help in replacing any import items currently
procured from outside India?
Does the technology have export potential? Yes
Category of Technology developed: Immediate Deployment
Stage of Development: Prototype Level
Please describe in detail including the TRL Level:
TRL6

    Abstract:

Applications: Various processes for preparation of warfarin acid, its salts are known in the literature using wide variations in solvents, acidic and basic catalysts, varying conditions like temperatures. However, the complexities involved in the preparation methods and the use of toxic chemicals like pyridine, costly reagents, complex organocatalysts make these processes unsatisfactory. The present technology produces a a simple, commercially feasible and direct preparation process of the end product in the pure state . Application: -Production of warfarin -Production of 3-SUBSTITUTED 4-HYDROXYCOUMARIN
Advantages: 1) Avoids use of toxic, organic solvent, rendering the process safe for environment and compounds produced. 2) Catalyst can be reused thereby making the process economical. 3) Avoids multiple steps.

    Technology Inputs:

Imported Equipment/Spare Parts:
Equipment/Spare Parts Year ITC-HS Code
NA
Indigenous Equipment/Spare Parts:
Equipment/Spare Parts Year ITC-HS Code
NA
Imported Raw Materials:
Raw Materials Year ITC-HS Code
NA
Indigenous Raw Materials:
Raw Materials Year ITC-HS Code
NA
Existing R&D Facilities used:
Facilities Year ITC-HS Code
NA

    R&D Investment:

R&D investment (Rs. in Lakhs):                    
Indian Source (Rs.) Foreign Source (Rs.) Year
0 0 NA

   Patents & Publications:

Patents:
Filed Patents (No.) Granted Patents (No.) Year
1 0 NA
Publications:
Submitted (No.) Published (No.) Year
0 0 NA

    Commercialization Potential:

Who are the Potential Licensees? Pharmaceutical Industry
What commercially available products address
the same problem?
Company Product Problem Addressed
Would you like to develop this invention further with
corporate research support?
Yes
Would you be interested in participating in cluster based
programs for commercialization research or business
planning for your invention?
Yes
      Submitted by: Anil Wali Date of Submission: 5-8-2020



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