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  Digital Catalogue for Technology and Products Development


   Technology and Product Development

    Basic Information

Technology developed: PROCESS FOR PREPARING THREE DIMENSIONAL POROUS SCAFFOLD (TP19763776039)
Category: Nil
Details of Inventor(s):
Inventor Institution/Organization/Company Department Designation
RAJIV KUMAR SRIVASTAVA IIT Delhi TEXTILE & FIBRE ENGINEERING Associate Professor
Technical Application Area: Healthcare
If 'Other', please specify:
Please give more details of new technical application area:
Organization(s):
Indian Institute of Technology (IIT) Delhi
Affiliated Ministry: Institution Funding (Self Supported)
Type of technology development: Indigenous
Does the technology help in replacing any import items currently
procured from outside India?
Does the technology have export potential? 1
Category of Technology developed: Immediate Deployment
Stage of Development: Lab-scale
Please describe in detail including the TRL Level:
TRL4

    Abstract:

Applications: Porous scaffolds of biodegradable polymers play an important role in tissue engineering to control cell functions and guide formation of new tissues and organs. Polymeric porous scaffolds are prepared using various techniques, most of which are multi-step processes and involve dissolution of preformed polymer into organic solvent or melting to develop the scaffold. In contrast, emulsion templating in the form of high internal phase emulsions (HIPE) is a single step process but it has been developed only for vinylic monomers in which polymerization is conducted using free radical polymerization methodology. Emulsion templating has not been carried out for cyclic monomers including lactones in which polymerization is via ring-opening. The current invention relates to formation of 3D porous scaffolds based on aliphatic polyesters via a single step ring opening polymerization process in a HIPE mode using sensitive catalysts in a non-inert atmosphere.
Advantages: 1. Polymerization of cyclic monomers e.g. lactones, lactides and carbonates under HIPE mode 2. Single-step process to obtain 3D porous scaffold 3. A 3D porous scaffold of intricate 3D shape is obtained which is suitable for variety of applications 4. A control on the pore size and interconnectedness is obtained by the process

    Technology Inputs:

Imported Equipment/Spare Parts:
Equipment/Spare Parts Year ITC-HS Code
NA
Indigenous Equipment/Spare Parts:
Equipment/Spare Parts Year ITC-HS Code
NA
Imported Raw Materials:
Raw Materials Year ITC-HS Code
NA
Indigenous Raw Materials:
Raw Materials Year ITC-HS Code
NA
Existing R&D Facilities used:
Facilities Year ITC-HS Code
NA

    R&D Investment:

R&D investment (Rs. in Lakhs):                    
Indian Source (Rs.) Foreign Source (Rs.) Year
0 0 NA

   Patents & Publications:

Patents:
Filed Patents (No.) Granted Patents (No.) Year
0 0 NA
Publications:
Submitted (No.) Published (No.) Year
0 0 NA

    Commercialization Potential:

Who are the Potential Licensees?
What commercially available products address
the same problem?
Company Product Problem Addressed
Would you like to develop this invention further with
corporate research support?
Yes
Would you be interested in participating in cluster based
programs for commercialization research or business
planning for your invention?
Yes
      Submitted by: Anil Wali Date of Submission: 5-8-2020



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