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  Digital Catalogue for Technology and Products Development


   Technology and Product Development

    Basic Information

Technology developed: INFECTION RESISTANT NANO-FUNCTIONAL POLYURETHANE MATERIAL (TP19764221806)
Category: Nil
Details of Inventor(s):
Inventor Institution/Organization/Company Department Designation
BHUVANESH GUPTA IIT Delhi TEXTILE & FIBRE ENGINEERING Professor
Technical Application Area: Healthcare
If 'Other', please specify:
Please give more details of new technical application area:
Organization(s):
Indian Institute of Technology (IIT) Delhi
Affiliated Ministry: Institution Funding (Self Supported)
Type of technology development: Indigenous
Does the technology help in replacing any import items currently
procured from outside India?
Does the technology have export potential? 1
Category of Technology developed: Immediate Deployment
Stage of Development: Lab-scale
Please describe in detail including the TRL Level:
TRL4

    Abstract:

Applications: There are several applications of infection resistant material in healthcare setting such as for making a urinary catheter. Urinary catheters are under constant drainage of urinary fluid and are a common source of nosocomial infections and other complications due to formation of biofilm. To inhibit such biofilms, it is important to protect and cover both inner and outer surfaces and antimicrobials used for this purpose should have no known history of significant toxicity. However, even antibiotics generally fail to act against such biofilms. Currently rubber, silicone, polyurethane and teflon catheters are available with specific properties. However, these do not provide effective protection against the infection as any modification in the material does not show effectiveness towards infection after long time of catherization. The present invention provides a highly flexible material with long durable antimicrobial nature and a process of preparing such a material. A method has been developed to functionalize a Polyurethane material by immobilizing different nature of bioactive agents i.e chlorhexidine digluconate (Clx), functional nanosilver and nano zinc oxide. The bioactive agents are released sustainably in different media through the polyurethane material and thus the antimicrobial property is for a longer duration. The resultant nano-functional material exhibits high flexibility, less friction and long durability with antimicrobial nature. Applications: 1. Medical device such as catheter 2. Antimicrobial surfaces
Advantages: 1. It is flexible. 2. It is bacteriostatic or bactericidal in nature. 3. It shows resistance to both gram positive and negative bacteria. 4. It shows complete reduction in bacterial growth. 5. It has good mechanical strength and decrease in stiffness, thus making it amendable. 6. The drug effectiveness is for 7-30 days depending upon the functionalization and agent, while in prior art effectiveness has been shown for 4 days.

    Technology Inputs:

Imported Equipment/Spare Parts:
Equipment/Spare Parts Year ITC-HS Code
NA
Indigenous Equipment/Spare Parts:
Equipment/Spare Parts Year ITC-HS Code
NA
Imported Raw Materials:
Raw Materials Year ITC-HS Code
NA
Indigenous Raw Materials:
Raw Materials Year ITC-HS Code
NA
Existing R&D Facilities used:
Facilities Year ITC-HS Code
NA

    R&D Investment:

R&D investment (Rs. in Lakhs):                    
Indian Source (Rs.) Foreign Source (Rs.) Year
0 0 NA

   Patents & Publications:

Patents:
Filed Patents (No.) Granted Patents (No.) Year
0 0 NA
Publications:
Submitted (No.) Published (No.) Year
0 0 NA

    Commercialization Potential:

Who are the Potential Licensees?
What commercially available products address
the same problem?
Company Product Problem Addressed
Would you like to develop this invention further with
corporate research support?
Yes
Would you be interested in participating in cluster based
programs for commercialization research or business
planning for your invention?
Yes
      Submitted by: Anil Wali Date of Submission: 5-8-2020



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