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   Technology and Product Development

    Basic Information

Technology developed: A Process for Sterilisation of Ultra-high Molecular Weight Polyethylene and its Nanocomposites (TP19764807873)
Category: Technology Service/Know how
Details of Inventor(s):
Inventor Institution/Organization/Company Department Designation
Chinmayee Nayak IIT Kanpur Material Science and Engineering Student
Ariharan S IIT Kanpur Material Science and Engineering Post Doc
Sneha Singh IIT Kanpur MAterial Science and Engineering Student
Kantesh Balani IIT Kanpur Material Science and Engineering Professor
Technical Application Area: Other
If 'Other', please specify:
Biomedical Engineering
Please give more details of new technical application area:
Organization(s):
Indian Institute of Technology (IIT) Kanpur
Affiliated Ministry: Ministry of Education
Type of technology development: Indigenous
Does the technology help in replacing any import items currently
procured from outside India?
Yes
Does the technology have export potential? Yes
Category of Technology developed: Immediate Deployment
Stage of Development: Field Test
Please describe in detail including the TRL Level:
Field test is being done

    Abstract:

Applications: A novel method for producing improved ultra-high molecular weight polyethylene (UHMWPE) and its nanocomposites (UHMWPE-alumina (Al2O3)-Hydroxyapatite (HAp)-carbon nanotubes (CNTs)) as acetabular cup liner in total hip joint replacement (THR). Sterilization of implants before surgery is inevitable, thus only UV and only Gamma-irradiation techniques have been used for standard sterilization. The novelty of the present invention is to sequence them i.e., first UV-irradiation followed by gamma-irradiation. The optimum sterilizing time is crucial as it controls the mechanical strength and wear resistance of PE composites. So, a range of treatment time is provided below which sterilization is not effective and above which deterioration in properties occurred due to chain scission.
Advantages: The sequentially sterilized (first UV, then Gamma) UHMWPE and its composites can be a suitable implant material for any joint surgery, more preferably articulating cup liner in hip joint replacement surgery. The superior mechanical strength and wear resistance of sequentially sterilized UHMWPE cup liner can improve the lifespan (greater than 15 years) of hip joint surgery in young patients. The novel sterilization method can be implemented to biomedical devices for cells proliferation and growth However, different polymers (Polyether ether ketone, Polytetrafluorethylene, high density polyethylene etc.) used in biomedical devices can be sequentially sterilized to modulate the surface or bulk molecular arrangement with improved mechanical strength and wear resistance.

    Technology Inputs:

Imported Equipment/Spare Parts:
Equipment/Spare Parts Year ITC-HS Code
NA
Indigenous Equipment/Spare Parts:
Equipment/Spare Parts Year ITC-HS Code
NA
Imported Raw Materials:
Raw Materials Year ITC-HS Code
NA
Indigenous Raw Materials:
Raw Materials Year ITC-HS Code
NA
Existing R&D Facilities used:
Facilities Year ITC-HS Code
NA

   Patents & Publications:

Patents:
Filed Patents (No.) Granted Patents (No.) Year
1 0 2020-21
Publications:
Submitted (No.) Published (No.) Year
0 1 2020-21

    Commercialization Potential:

Who are the Potential Licensees? Orthotech India, XL Orthomed Pvt. Ltd., Zimmer Biomet, Stryker orthopedics, Wright medical group
What commercially available products address
the same problem?
Company Product Problem Addressed
Would you like to develop this invention further with
corporate research support?
Yes
Would you be interested in participating in cluster based
programs for commercialization research or business
planning for your invention?
Yes
      Submitted by: J.G. Rao Date of Submission: 8-3-2022



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