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   Technology and Product Development

    Basic Information

Technology developed: Vaccine: VSV based live attenuated recombinant vaccine against Novel Coronavirus infectionsystems (TP19767041765)
Category: Product(Hardware/Material/Software)
Details of Inventor(s):
Inventor Institution/Organization/Company Department Designation
Dr. Dibyendu Kumar Das Indian Institute of Technology (IIT) Kanpur Department of Biological Sciences and Bioengineeri
Technical Application Area: Covid-19 technologies
If 'Other', please specify:
Please give more details of new technical application area:
Organization(s):
Affiliated Ministry: Institution Funding (Self Supported)
Type of technology development: Indigenous
Does the technology help in replacing any import items currently
procured from outside India?
Yes
Does the technology have export potential? Yes
Category of Technology developed: Immediate Deployment
Stage of Development: Commercialized
Please describe in detail including the TRL Level:
Done.

    Abstract:

Applications: Dr. Dibyendu Kumar Das, Department of Biological Sciences and Bioengineering, IIT Kanpur and his team have aimed to develop replication-competent vaccines against Novel coronavirus (SARS-CoV-2) based on attenuated recombinant vesicular stomatitis virus (rVSV) vectors expressing the novel corona virus spike (s) glycoprotein (rVSV SARS CoV 2S). Vaccines, designed on live attenuated recombinant VSV template have been highly effective in animal models and are particularly appealing because they can be administered mucosally. Additionally, VSV rarely infect human and the chance of infection due to VSV is negligible. Recently, recombinant VSV based Ebola virus, Marburg virus and Lassa virus vaccine has been developed and tested effective in nonhuman primates model.
Advantages: The rVSV ZEBOV GP vaccine against Ebola had been 97.5 percent effective at stopping Ebola transmission, relative to no vaccination, approved by WHO in 2019 for vaccination.

    Technology Inputs:

Imported Equipment/Spare Parts:
Equipment/Spare Parts Year ITC-HS Code
NA
Indigenous Equipment/Spare Parts:
Equipment/Spare Parts Year ITC-HS Code
NA
Imported Raw Materials:
Raw Materials Year ITC-HS Code
NA
Indigenous Raw Materials:
Raw Materials Year ITC-HS Code
NA
Existing R&D Facilities used:
Facilities Year ITC-HS Code
NA

   Patents & Publications:

Patents:
Filed Patents (No.) Granted Patents (No.) Year
0 0 NA
Publications:
Submitted (No.) Published (No.) Year
0 0 NA

    Commercialization Potential:

Who are the Potential Licensees?
What commercially available products address
the same problem?
Company Product Problem Addressed
Would you like to develop this invention further with
corporate research support?
No
Would you be interested in participating in cluster based
programs for commercialization research or business
planning for your invention?
No
      Submitted by: I-STEM Admin Date of Submission: 27-4-2023



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