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  Digital Catalogue for Technology and Products Development


   Technology and Product Development

    Basic Information

Technology developed: Deciphering The Bmp Signaling Network In Developing Bone (TP19767776448)
Category: Technology Service/Know how
Details of Inventor(s):
Inventor Institution/Organization/Company Department Designation
Prof. Amitabha Bandyopadhyay Indian Institute of Technology (IIT) Kanpur Biological Sciences and Bioengineering
Prof. Harish Karnick, Indian Institute of Technology (IIT) Kanpur Biological Sciences and Bioengineering
Prof. Arnab Bhattacharya, Indian Institute of Technology (IIT) Kanpur Biological Sciences and Bioengineering
Prof. Madhav Ranganathan. Indian Institute of Technology (IIT) Kanpur Biological Sciences and Bioengineering
Technical Application Area: Biotechnology
If 'Other', please specify:
Please give more details of new technical application area:
Organization(s):
Indian Institute of Technology (IIT) Kanpur
Affiliated Ministry: Institution Funding (Self Supported)
Type of technology development: Indigenous
Does the technology help in replacing any import items currently
procured from outside India?
Yes
Does the technology have export potential? Yes
Category of Technology developed: Immediate Deployment
Stage of Development: Prototype Level
Please describe in detail including the TRL Level:
Ready

    Abstract:

Applications: Bone Morphogenetic Proteins BMPs are secrete signaling molecules that dictate bone formation. There is evidence suggesting that loss of BMPs may lead to osteoporosis. Thus BMP signaling is a possible therapeutic target for osteoporosis. The project aims to characterize the molecular network acting downstream of BMP signaling to promote bone formation. This is proposed to be achieved by an interdisciplinary approach combining bioinformatics data mining, transcriptomic analyses and functional assays using novel in house developed cell lines and network construction simulation.
Advantages: Bone Morphogenetic Proteins BMPs are secrete signaling molecules that dictate bone formation. There is evidence suggesting that loss of BMPs may lead to osteoporosis. Thus BMP signaling is a possible therapeutic target for osteoporosis. The project aims to characterize the molecular network acting downstream of BMP signaling to promote bone formation. This is proposed to be achieved by an interdisciplinary approach combining bioinformatics data mining, transcriptomic analyses and functional assays using novel in house developed cell lines and network construction simulation.

    Technology Inputs:

Imported Equipment/Spare Parts:
Equipment/Spare Parts Year ITC-HS Code
NA
Indigenous Equipment/Spare Parts:
Equipment/Spare Parts Year ITC-HS Code
NA
Imported Raw Materials:
Raw Materials Year ITC-HS Code
NA
Indigenous Raw Materials:
Raw Materials Year ITC-HS Code
NA
Existing R&D Facilities used:
Facilities Year ITC-HS Code
NA

   Patents & Publications:

Patents:
Filed Patents (No.) Granted Patents (No.) Year
0 0 NA
Publications:
Submitted (No.) Published (No.) Year
0 0 NA

    Commercialization Potential:

Who are the Potential Licensees?
What commercially available products address
the same problem?
Company Product Problem Addressed
Would you like to develop this invention further with
corporate research support?
Yes
Would you be interested in participating in cluster based
programs for commercialization research or business
planning for your invention?
Yes
      Submitted by: Technical Team Date of Submission: 1-5-2023



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