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  Digital Catalogue for Technology and Products Development

   Technology and Product Development

    Basic Information

Technology developed: Polydimethylsiloxane Nanoparticles Coated Scaffolds for Culturing Cells and Tissue Engineering (TP19769614511)
Category: Product(Hardware/Material/Software)
Details of Inventor(s):
Inventor Institution/Organization/Company Department Designation
Dr. Sri Sivakumar IIT Kanpur Chemical Engineering Faculty Member
Mr. Auhin Kumar Maparu IIT Kanpur Chemical Engineering Student
Ms. Prerana Singh IIT Kanpur Biological Sciences & Bioengineering Student
Ms. Beena Rai Tata Consultancy Services Collaborator
Technical Application Area: Biotechnology
If 'Other', please specify:
Please give more details of new technical application area:
Indian Institute of Technology (IIT) Kanpur
Tata Consultancy Services
Affiliated Ministry: MHRD, Govt. of India
Type of technology development: Indigenous
Does the technology help in replacing any import items currently
procured from outside India?
Does the technology have export potential? 1
Category of Technology developed: Futuristic
Stage of Development: Lab-scale
Please describe in detail including the TRL Level:
TRL Level 5


Applications: 1. The current invention relates to methods and compositions to make nanoparticles-coated scaffolds by coating two-dimensional or three-dimensional scaffolds with polydimethylsiloxane nanoparticles. 2. The invention discloses the uses of these nanoparticles-coated scaffolds for culturing mammalian cells and for tissue engineering, such as exhibiting increased cellular adhesion, growth and proliferation as compared to scaffolds not coated with the polydimethylsiloxane nanoparticles. 3. The invention also discloses the use of the polydimethylsiloxane nanoparticles-coated scaffolds for skin tissue engineering.
Advantages: 1. The current invention discloses compositions and methods for making nanoparticles coated scaffold for cell-culture and tissue engineering, the nanoparticles-coated scaffold comprising a scaffold coated with polydimethylsiloxane (PDMS) nanoparticles. 2. One embodiment of the invention is a nanoparticles-coated scaffold comprising a scaffold coated with PDMS nanoparticles, wherein the nanoparticles-coated scaffold is used for culturing mammalian cells. In one embodiment, the nanoparticles-coated scaffold described herein is used for tissue engineering. 3. In one embodiment, the nanoparticles coated scaffold described herein is used for skin tissue engineering. In one embodiment, the nanoparticles-coated scaffold described herein exhibits increase in cell adhesion, cell growth and cell differentiation properties compared to a scaffold that is not coated with PDMS nanoparticles. 4. In one embodiment, the scaffold used for making the nanoparticles-coated scaffold described herein is two-dimensional (2D) or three-dimensional (3D).

    Technology Inputs:

Imported Equipment/Spare Parts:
Equipment/Spare Parts Year ITC-HS Code
Indigenous Equipment/Spare Parts:
Equipment/Spare Parts Year ITC-HS Code
Imported Raw Materials:
Raw Materials Year ITC-HS Code
Indigenous Raw Materials:
Raw Materials Year ITC-HS Code
Existing R&D Facilities used:
Facilities Year ITC-HS Code

    R&D Investment:

R&D investment (Rs. in Lakhs):                    
Indian Source (Rs.) Foreign Source (Rs.) Year
0 0 NA

   Patents & Publications:

Filed Patents (No.) Granted Patents (No.) Year
1 0 2019-20
Submitted (No.) Published (No.) Year
0 0 NA

    Commercialization Potential:

Who are the Potential Licensees?
What commercially available products address
the same problem?
Company Product Problem Addressed
Would you like to develop this invention further with
corporate research support?
Would you be interested in participating in cluster based
programs for commercialization research or business
planning for your invention?
      Submitted by: Tarun Gupta Date of Submission: 4-8-2020

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