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Applicant:
Indian Institute of Technology (IIT) Gandhinagar 
Title:
PHARMACEUTICAL COMPOUND AND PROCESS FOR PREPARING THE SAME 
Inventor(s):
KIRUBAKARAN Sivapriya, RAVI Srimadhavi, SHAIK Althaf, BARUI Sugata 
Applicant:
Indian Institute of Technology (IIT) Gandhinagar 
Application type:
Applied - 2018-10-19 
Application Number:
201821039653 
Applied at:
India 
Entered by:
Indian Institute of Technology (IIT) Gandhinagar 
Abstract:
The present disclosure relates to a quinoline based compounds and a process for preparing the same. The Quinoline based compounds have pharmacokinetic and pharmacodynamics properties which make them potential inhibitors of the PIKK family of kinases, especially ATM, ATR, and DNA-PKcs, which play a vital role in the survival of cancer cells. These quinoline based compounds have a potential to kill the cancer cells preferentially by exploiting the concept of synthetic lethality. 

 
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