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Patent Details

Applicant:
Indian Institute of Technology (IIT) Roorkee 
Title:
Fluorescence based cost-effective rapid diagnostic kit for detection of cancer biomarkers 
Inventor(s):
P. Gopinath, Ashish and Rangadhar Pradha 
Applicant:
Indian Institute of Technology (IIT) Roorkee 
Application type:
Applied - 2020-03-09 
Application Number:
202011010110 
Applied at:
India 
Entered by:
Indian Institute of Technology (IIT) Roorkee 
Abstract:
The present invention relates to a fluorescence based rapid diagnostic kit for highly sensitive detection of cancer cell-specific biomarkers utilizing biofunctionalized graphene quantum dots as donor and gold nanoparticles as acceptor in a fluorescence based assay. The invention discloses a kit for detection of cancer biomarkers, more specifically, of small cell lung cancer biomarker by using anti-neuron specific enolase antibody conjugated to amine functionalized nitrogen doped graphene quantum dots. The invention is directed to methods and compositions for making the diagnostic kit. The novel process discloses one-pot, low temperature, and the bottom-up hydrothermal route for the synthesis of in-situ amine-functionalized and nitrogen-doped graphene quantum dots. 

 
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It has always been the basic tenet of the Government of India, in generously funding R&D efforts at academic institutions over the years, that facilities established through such support be made available to those needing them and qualified to make use of them for their own research work
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However, this was never easy or straightforward for, among other reasons, there was no ready source of information of what facility was available and where. Thanks to the Web, it is much easier today to have a national and regional “inventory of resources”, so as to match users with the resources they need, and to do all this in an efficient and transparent manner.

This can lead to a leap in R&D productivity and greatly enhance the effectiveness of public investment. This is the motivation behind I-STEM.
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