Indian Science Technology and Engineering facilities Map
Supplier Map
Service Map

Publications

Publication Details

Applicant:
Indian Institute of Technology (IIT) Patna 
Author:
Tasneem Parvin, Rahul Yadav and Lokman H. Choudhury,  
Corresponding Authors:
Lokman H. Choudhury 
DOI #:
https://doi.org/10.1039/D0OB00595A 
Title:
Recent applications of thiourea-based organocatalysts in asymmetric multicomponent reactions (AMCRs) 
Journal:
Organic & Biomolecular Chemistry 
Year:
2020 
Volume:
NA 
Page:
NA 
Keywords:
thiourea-based organocatalysts, asymmetric multicomponent reactions (AMCRs) 
Abstract:
One-pot multiple bond-forming reactions under metal-free conditions have tremendous potential in organic and medicinal chemistry considering their synthetic efficiency and eco-friendliness. In this direction, organocatalysis, i.e. application of organic molecules as catalysts, in multicomponent reactions is one of the best combinations for the preparation of complex molecules in minimum steps under green reaction conditions. Thiourea-based organic molecules show excellent catalytic activity in various transformations by their unique double H-bonding activation process. Chiral organic molecules having a thiourea backbone are well-recognized catalysts for the enantioselective synthesis of diverse products from asymmetric two- or multicomponent reactions. Simultaneous dual activation of the electrophile and the nucleophile in an MCR by using bifunctional thiourea-based chiral organocatalysts has gained considerable interest in recent times. Although several review articles are available in the literature on organocatalysis, asymmetric domino reactions, or multicomponent reactions using various organocatalysts, however, to date there has been no dedicated review article on this emerging topic, i.e. asymmetric multicomponent reactions catalysed by thiourea-based organocatalysts. Thus, this review aims to highlight the recent applications of thiourea-based organocatalysts in asymmetric multicomponent reactions. 
Entered by:
Venkata Dantham on 2020-08-04 
 
I-Mitra(आई-मित्र) Welcomes You..
THE VISION
THE MISSION
ABOUT I-STEM
It has always been the basic tenet of the Government of India, in generously funding R&D efforts at academic institutions over the years, that facilities established through such support be made available to those needing them and qualified to make use of them for their own research work
read more >>

However, this was never easy or straightforward for, among other reasons, there was no ready source of information of what facility was available and where. Thanks to the Web, it is much easier today to have a national and regional “inventory of resources”, so as to match users with the resources they need, and to do all this in an efficient and transparent manner.

This can lead to a leap in R&D productivity and greatly enhance the effectiveness of public investment. This is the motivation behind I-STEM.
read less <<
Visitor Hit Counter
Hosted at Indian Institute of Science
Copyright © 2020 I-STEM. All rights reserved.
Audited by: STQC Bengaluru.