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Applicant:
Indian Institute of Technology (IIT) Patna 
Author:
Maji, S.K., Yahia, H.  
Corresponding Authors:
Suman Kumar Maji 
DOI #:
10.1038/s41598-019-43973-2 
Title:
A Feature based Reconstruction Model for Fluorescence Microscopy Image Denoising 
Journal:
Scientific Reports 
Year:
2019 
Volume:
9( 1 ) 
Page:
NA 
Keywords:
Fluorescence Microscopy Image 
Abstract:
The advent of Fluorescence Microscopy over the last few years have dramatically improved the problem of visualization and tracking of specific cellular objects for biological inference. But like any other imaging system, fluorescence microscopy has its own limitations. The resultant images suffer from the effect of noise due to both signal dependent and signal independent factors, thereby limiting the possibility of biological inferencing. Denoising is a class of image processing algorithms that aim to remove noise from acquired images and has gained wide attention in the field of fluorescence microscopy image restoration. In this paper, we propose an image denoising algorithm based on the concept of feature extraction through multifractal decomposition and then estimate a noise free image from the gradients restricted to these features. Experimental results over simulated and real fluorescence microscopy data prove the merit of the proposed approach, both visually and quantitatively. 
Entered by:
Venkata Dantham on 2020-08-04 
 
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