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Applicant:
Central University of Tamil Nadu 
Author:
S. Sathishkumar, L. Kavitha, E. Shinyjoy and D. Gopi 
Corresponding Authors:
D. Gopi 
DOI #:
doi.org/10.1021/acs.iecr.5b04329 
Title:
Tailoring the Sm/Gd-Substituted Hydroxyapatite Coating on Biomedical AISI 316L SS: Exploration of Corrosion Resistance, Protein Profiling, Osteocompatibility, and Osteogenic Differentiation for Orthopedic Implant Applications 
Journal:
Industrial & Engineering Chemistry Research 
Year:
2016 
Volume:
55 
Page:
6331–6344 
Keywords:
316L SS stainless steel; substituted hydroxyapatite; anticorrosion behavior; bone tissue regeneration  
Abstract:
In this paper, we have fabricated the samarium/gadolinium-substituted hydroxyapatite (Sm/Gd-HAP) coating on the borate-passivated AISI 316L SS stainless steel. The structural and morphological characteristics of the Sm/Gd-HAP coatings were investigated using various analytical techniques and the anticorrosion behavior of the coating was studied through electrochemical techniques. The antibacterial activity of the coating was tested against Staphylococcus aureus and Escherichia coli bacterial stains and, in particular, S. aureus showed better sensitivity toward the Sm/Gd-HAP coating, which might be due to the Sm substitution in the coating. The in vitro cytotoxicity and biocompatibility of the as-developed coating on passivated AISI 316L SS were investigated using MC3T3-E1 cell line, which exhibited a high cell proliferation rate and provided significantly higher cell viability. Thus, the resultant Sm/Gd-HAP coating on passivated AISI 316L SS could be considered to be an effective bioimplant for bone tissue regeneration applications. 
Entered by:
Kavitha Louis on 2020-09-03 
 
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