Indian Science Technology and Engineering facilities Map
 
Supplier Map
Service Map

Publications

Publication Details

Applicant:
Central University of Tamil Nadu 
Author:
Indranil Chattopadhyay 
Corresponding Authors:
Indranil Chattopadhyay 
DOI #:
DOI: 10.4103/jrcr.jrcr_8_17 
Title:
Application of radiogenomics in radiation oncology 
Journal:
Journal of Radiation and Cancer Research 
Year:
2017 
Volume:
Page:
74-76 
Keywords:
Radiation, genomics, cancer, therapy 
Abstract:
Radiotherapy (RT) can be used in the treatment of cancers, instead of surgery to achieve better functional results by using external beam RT and brachytherapy. Elevation of radiation response in tumor cells and reduction of sensitivity to radiation in adjacent normal tissues are the core issues in the radiotherapeutic field of tumor. Radiogenomics addresses possible associations between germline genetic variation and normal tissue toxicity after RT. The objective of radiation genomics is to identify the genetic markers for personalized RT, in which cancer management is formulated so that the treatment plan will be optimized for each patient based on their genetic background. Combinatorial approaches to radiation-induced gene expression study and genome-wide SNP genotype study may discover candidate biomarkers for personalization of RT treatment and identify genetic alterations that affect risk of normal tissue toxicity. 
Entered by:
Indranil Chattopadhyay on 2020-09-03 
 
THE VISION
THE MISSION
ABOUT I-STEM
It has always been the basic tenet of the Government of India, in generously funding R&D efforts at academic institutions over the years, that facilities established through such support be made available to those needing them and qualified to make use of them for their own research work
read more >>

However, this was never easy or straightforward for, among other reasons, there was no ready source of information of what facility was available and where. Thanks to the Web, it is much easier today to have a national and regional “inventory of resources”, so as to match users with the resources they need, and to do all this in an efficient and transparent manner.

This can lead to a leap in R&D productivity and greatly enhance the effectiveness of public investment. This is the motivation behind I-STEM.
read less <<
Visitor Hit Counter
Hosted at Indian Institute of Science
Copyright © 2024 I-STEM. All rights reserved.
Audited by: STQC Bengaluru.