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   Technology and Product Development

    Basic Information

Technology developed: Oral DPT Vaccine (TP19763358557)
Category: Product(Hardware/Material/Software)
Details of Inventor(s):
Inventor Institution/Organization/Company Department Designation
Dr. Pooja Doshi Savitribai Phule Pune University Design Innovation Centre Asst. Professor
Mr. Gopal Srivastava Savitribai Phule Pune University Design Innovation Centre Research Fellow
Technical Application Area: Healthcare
If 'Other', please specify:
Please give more details of new technical application area:
The research are in collaboration with Serum Institute of India Ltd.
Organization(s):
Savitribai Phule Pune University Pune
Affiliated Ministry: MHRD, Govt. of India
Type of technology development: Indigenous
Does the technology help in replacing any import items currently
procured from outside India?
No
Does the technology have export potential? Yes
Category of Technology developed: Futuristic
Stage of Development: Prototype Level
Please describe in detail including the TRL Level:
The general stages of the development cycle of a vaccine are: 1) Exploratory stage 2) Pre-clinical stage 3) Clinical development 4) Regulatory review and approval 5) Manufacturing 6) Quality control We are at Pre-clinical stage and further collabration with suitable enterprises are required for advanced of the developed formulation.

    Abstract:

Applications: Oral vaccination to mass population of developing countries like India for any age groups of patients.
Advantages: Oral dose of DPT vaccine is required due to inherent problem associated with injectable DPT and their advantages are as follows: 1. Reduces pain and discomfort 2. Risk of infection 3. No need of trained person for administration 4. Avoid fear of injection in Indian rural population

    Technology Inputs:

Imported Equipment/Spare Parts:
Equipment/Spare Parts Year ITC-HS Code
NA
Indigenous Equipment/Spare Parts:
Equipment/Spare Parts Year ITC-HS Code
NA
Imported Raw Materials:
Raw Materials Year ITC-HS Code
Water soluble chitosan 2015-16 39069090
Water soluble chitosan 2016-17 39069090
Sodium tripolyphosphate 2017-18 28353100
Sodium tripolyphosphate 2018-19 28353100
Sodium tripolyphosphate 2015-16 28353100
Sodium tripolyphosphate 2016-17 28353100
Sodium tripolyphosphate 2017-18 28353100
Sodium tripolyphosphate 2018-19 28353100
Sodium tripolyphosphate 2015-16 28353100
Sodium tripolyphosphate 2016-17 28353100
Sodium tripolyphosphate 2017-18 28353100
Sodium tripolyphosphate 2018-19 28353100
Water soluble chitosan 2017-18 39069090
Water soluble chitosan 2018-19 39069090
Sodium tripolyphosphate 2015-16 28353100
Sodium tripolyphosphate 2016-17 28353100
Sodium tripolyphosphate 2017-18 28353100
Sodium tripolyphosphate 2018-19 28353100
Sodium tripolyphosphate 2015-16 28353100
Sodium tripolyphosphate 2016-17 28353100
Indigenous Raw Materials:
Raw Materials Year ITC-HS Code
Vanillin 2016-17 29124100
Vanillin 2017-18 29124100
Tetanus Toxoid 2018-19 30041090
Diptheria Toxoid 2016-17 30022021
Diptheria Toxoid 2017-18 30022021
Diptheria Toxoid 2018-19 30022021
Whole Cell Pertussis 2017-18 30022029
Whole Cell Pertussis 2018-19 30022029
Vanillin 2018-19 29124100
Tetanus Toxoid 2015-16 30041090
Tetanus Toxoid 2016-17 30041090
Tetanus Toxoid 2017-18 30041090
Existing R&D Facilities used:
Facilities Year ITC-HS Code
Infrared spectrophotometer 2015-16 90273020
Infrared spectrophotometer 2016-17 90273020
Thermo Gravimetric Analyser 2018-19 90278090
Multi-Mode Microplate Readers 2016-17 90275090
Scanning Electron Microscope 2016-17 90121090
Multi-Mode Microplate Readers 2017-18 90275090
Fine weighing balance 2016-17 90160010
Infrared spectrophotometer 2017-18 90273020
Fine weighing balance 2017-18 90160010
U-V Visible Spectrophotometer 2016-17 90273020
X-ray Diffractometer 2016-17 90221900
U-V Visible Spectrophotometer 2017-18 90273020
X-ray Diffractometer 2018-19 90221900
Scanning Electron Microscope 2015-16 90121090
Scanning Electron Microscope 2017-18 90121090
Thermo Gravimetric Analyser 2017-18 90278090
Scanning Electron Microscope 2018-19 90121090
Infrared spectrophotometer 2018-19 90273020
particle size and zeta potential analyzer 2017-18 90278090
X-ray Diffractometer 2015-16 90221900
X-ray Diffractometer 2017-18 90221900
Thermo Gravimetric Analyser 2015-16 90278090
Fine weighing balance 2015-16 90160010
Thermo Gravimetric Analyser 2016-17 90278090
particle size and zeta potential analyzer 2015-16 90278090
U-V Visible Spectrophotometer 2015-16 90273020
particle size and zeta potential analyzer 2016-17 90278090
Multi-Mode Microplate Readers 2015-16 90275090

    R&D Investment:

R&D investment (Rs. in Lakhs):                    
Indian Source (Rs.) Foreign Source (Rs.) Year
830000 0 2015-16
1010000 0 2016-17
1250000 0 2017-18
400000 0 2018-19
150000 0 2019-20

   Patents & Publications:

Patents:
Filed Patents (No.) Granted Patents (No.) Year
0 0 NA
Publications:
Submitted (No.) Published (No.) Year
0 1 2015-16
0 1 2016-17
0 1 2018-19

    Commercialization Potential:

Who are the Potential Licensees? 1..Serum Institute of India, 212/2, Hadapsar, Pune- 411028 2. Bharat biotech International Ltd, Genome Valley, Turka-pally (V), ShameerpetMandal, Ranga Reddy District, Hyderabad 3. Biological E., 18/1 &3, Azamabad, Hyderabad-500020 Andhra Pradesh 4.Biological E., Plot No.1, S.P. Biotechnology Park, Phase-II, Kolthur Village, Shameerpet Mandal 5. Panacea, Malpur, Baddi, PO Bhud, Tehsil, Nalagarh, Distt. Solan, (H.P) 6.Shantha Biotechnics Ltd. survey No. 274, Athvelli Village, medchal Mandal, Ranga Reddy, District-501401 7.Human biological institutute, Rakshapuram, Gaachibowli, Hyderabad-500032 8.HLL Biotech Ltd., Ticel Biopark Campus, CSIR Road, Taramani, Chennai 9.CRI, Kasauli, District Solan, HP. 10. Pasteur institute of India, Coonor- 643103, Nilgiris District, Tamil Nadu
What commercially available products address
the same problem?
Company Product Problem Addressed
Would you like to develop this invention further with
corporate research support?
Yes
Would you be interested in participating in cluster based
programs for commercialization research or business
planning for your invention?
Yes
      Submitted by: Arvind D Shaligram Date of Submission: 4-8-2020



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