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  Digital Catalogue for Technology and Products Development


   Technology and Product Development

    Basic Information

Technology developed: Herbal Formulation for Sickle Cell Disease (TP19769113865)
Category: Product(Hardware/Material/Software)
Details of Inventor(s):
Inventor Institution/Organization/Company Department Designation
Dr Pooja Doshi Savitribai Phule Pune University Design Innovation Centre Assistant Professor
Mr Nitin Kadam Savitribai Phule Pune University Design Innovation Centre Project Technical Assistant
Mr Yuvraj Kale Savitribai Phule Pune University Design Innovation Centre Research Fellow
Technical Application Area: Healthcare
If 'Other', please specify:
Please give more details of new technical application area:
Organization(s):
Savitribai Phule Pune University Pune
Affiliated Ministry: Ministry of Education
Type of technology development: Indigenous
Does the technology help in replacing any import items currently
procured from outside India?
Yes
Does the technology have export potential? Yes
Category of Technology developed: Export Potential
Stage of Development: Lab-scale
Please describe in detail including the TRL Level:
TRL Level 4 The development of Sickle Cell Herbal Formulation product is done at laboratory scale and the product development is under pilot study implementation and planning for commercialization of formulation

    Abstract:

Applications: This product will act as a relief in pain crisis of Sickle Cell Disorder This product is an effective botanical drug formulation as antisickling agent and it has a potential use in managing overall pathophysiology in Sickle Cell Disease The herbal drug composition prepared has good polymerization inhibition activity and increased affinity to oxygen thereby useful for hypoxia and helps in overall management in Sickle Cell disease and a potential Antisickling agents
Advantages: The herbal drug composition has individual and synergistic pharmacological potential for overall management of cascades of pathophysiological conditions prevalent in the Sickle Cell Disease It protects the oxidative stress produced in Sickle Cell RBCs by antioxidant property of the herbal drug formulation thereby increase in the life span of Sickle Cell RBCs Overall this formulation may lead to decrease in the pathophysiological conditions and provides benefits for lethal manifestation in SCD

    Technology Inputs:

Imported Equipment/Spare Parts:
Equipment/Spare Parts Year ITC-HS Code
NA
HPTLC 2018-19 90272000
HPTLC 2018-19 90272000
Waters HPLC 2019-20 85238090
Waters HPLC 2017-18 85238090
Waters HPLC 2018-19 85238090
GCMS 2019-20 90272000
GCMS 2017-18 90272000
GCMS 2018-19 90272000
LCMS 2019-20 90272000
LCMS 2019-20 90272000
LCMS 2017-18 90272000
FTIR 2018-19 90273020
FTIR 2019-20 90273020
FTIR 2017-18 90273020
UV Visible Spectrophotometer 2018-19 90273020
UV Visible Spectrophotometer 2019-20 90273020
UV Visible Spectrophotometer 2017-18 90273020
Indigenous Equipment/Spare Parts:
Equipment/Spare Parts Year ITC-HS Code
NA
Imported Raw Materials:
Raw Materials Year ITC-HS Code
NA
Indigenous Raw Materials:
Raw Materials Year ITC-HS Code
Thinopyrum intermedium 2017-18 11043000
Thinopyrum intermedium 2018-19 11043000
Punica granatum 2019-20 08109010
Punica granatum 2020-21 08109010
Punica granatum 2017-18 08109010
Punica granatum 2018-19 08109010
Rubia cordifolia 2019-20 12119049
Rubia cordifolia 2020-21 12119049
Rubia cordifolia 2019-20 12119049
Rubia cordifolia 2020-21 12119049
Aegle marmelos 2017-18 06031900
Aegle marmelos 2018-19 06031900
Aegle marmelos 2019-20 06031900
Aegle marmelos 2020-21 06031900
Hydroxyurea Commercial Product 2017-18 30049099
Hydroxyurea Commercial Product 2018-19 30049099
Hydroxyurea Commercial Product 2019-20 30049099
Hydroxyurea Commercial Product 2020-21 30049099
Thinopyrum intermedium 2017-18 11043000
Thinopyrum intermedium 2018-19 11043000
Existing R&D Facilities used:
Facilities Year ITC-HS Code
NA

    R&D Investment:

R&D investment (Rs. in Lakhs):                    
Indian Source (Rs.) Foreign Source (Rs.) Year
200000 0 2017-18
400000 0 2018-19
350000 0 2019-20
250000 0 2020-21

   Patents & Publications:

Patents:
Filed Patents (No.) Granted Patents (No.) Year
0 1 2019-20
Publications:
Submitted (No.) Published (No.) Year
0 2 2019-20

    Commercialization Potential:

Who are the Potential Licensees? Costco Kroger Pharmacy Our possible collaboration is with Om Herbotach Gujrat India
What commercially available products address
the same problem?
Company Product Problem Addressed
Would you like to develop this invention further with
corporate research support?
Yes
Would you be interested in participating in cluster based
programs for commercialization research or business
planning for your invention?
Yes
      Submitted by: Arvind D Shaligram Date of Submission: 6-8-2020



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