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Patent Details

Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) Bengaluru 
Cationic Antibacterial Compound, Composition, Method and Articles Thereof  
Jayanta Haldar, Yarlagadda Venkateswarlu, Akkapeddi Padma 
Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) Bengaluru 
Application type:
Granted - 2018-05-03 
Application Number:
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Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) Bengaluru 
The present invention relates to the field of medicinal chemistry and more particularly to the development of antibacterial compounds. The present invention provides compounds that are cationic vancomycin analogues and their compositions. Said analogues of vancomycin provide enhanced efficacy against gram positive bacteria as compared to vancomycin and extend spectrum of activity to gram-negative bacteria and drug-resistant bacteria. Further, method of making the compounds and, articles comprising the compositions composed of said compounds are disclosed. Said compounds, compositions and articles have application in treatment of bacterial infection. 

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