| | | | | | | |
                
Indian Science Technology and Engineering facilities Map
Supplier Map
Service Map










Publications

Publication Details

Applicant:
Central University of Tamil Nadu 
Author:
Srinivasan Sampath 
Corresponding Authors:
Srinivasan Sampath, Debasis Samanta 
DOI #:
10.1007/s42452-019-0371-1 
Title:
Microcapsules responsive to pH and temperature: synthesis, encapsulation and release study 
Journal:
SN Applied Sciences 
Year:
2019 
Volume:
Page:
448 
Keywords:
Graphene oxide, Thermoresponsive, pH responsive, Polymers, Drug delivery 
Abstract:
In this present article, we report preparation of dual responsive microcapsules by using poly(N-isopropyl acrylamide-comethacrylic acid) [poly(NIPAM-co-MAA)] and acid functionalized graphene oxide (GO). While the methacrylic acid part is responsible for the responsiveness towards the change in pH, N-isopropylacrylamide part is responsible for the responsiveness towards change in temperatures. Functionalized GO forms the core of the microcapsules and its interaction with the polymer controls the movement of the encapsulated materials in response to change in neighboring environment. Surface morphology and interconnectivity of the microcapsules was observed by optical polarized microscopy and the presence of the GO sheets on the wall was observed in High Resolution Transmission Electron Microscopy images. The pH and temperature responsive nature of the microcapsules were studied by loading vitamin B2 or anticancer drug cisplatin. It was found that both pH and temperature influences releasing pattern of the either drug from microcapsule. 
Entered by:
Srinivasan Sampath on 2020-09-01 
 
THE VISION
THE MISSION
ABOUT I-STEM
It has always been the basic tenet of the Government of India, in generously funding R&D efforts at academic institutions over the years, that facilities established through such support be made available to those needing them and qualified to make use of them for their own research work
read more >>

However, this was never easy or straightforward for, among other reasons, there was no ready source of information of what facility was available and where. Thanks to the Web, it is much easier today to have a national and regional “inventory of resources”, so as to match users with the resources they need, and to do all this in an efficient and transparent manner.

This can lead to a leap in R&D productivity and greatly enhance the effectiveness of public investment. This is the motivation behind I-STEM.
read less <<
Visitor Hit Counter
Toll Free Number : 1800 425 3281
Hosted at Indian Institute of Science
Copyright © 2019 I-STEM. All rights reserved    Audited by: STQC Bengaluru.