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Applicant:
Central University of Tamil Nadu 
Author:
D. Gopi, K. Kanimozhi, L. Kavitha 
Corresponding Authors:
D. Gopi 
DOI #:
doi.org/10.1016/j.saa.2015.01.039 
Title:
Opuntia ficus indica peel derived pectin mediated hydroxyapatite nanoparticles: Synthesis, spectral characterization, biological and antimicrobial activities 
Journal:
SpectrochimicaActa part A: Molecular and Biomolecular Spectroscopy 
Year:
2015 
Volume:
141 
Page:
135–143 
Keywords:
Hydroxyapatite, Nanoparticles, Green route, Opuntia ficus indica, Bioactivity,Simulated body fluid 
Abstract:
In the present study, we have adapted a facile and efficient green route for the synthesis of HAP nanoparticles using pectin as a template which was extracted from the peel of prickly pear (Opuntia ficus indica) fruits. The concentration of pectin plays a major role in the behavior of crystallinity, purity, morphology as well as biological property of the as-synthesized HAP nanoparticles. The extracted pectin and the as-synthesized nanoparticles were characterized by various analytical techniques. The in vitro apatite formation on the surface of the as-synthesized nanoparticles in simulated body fluid (SBF) for various days showed an enhanced bioactivity. Also, the antimicrobial activity was investigated using various microorganisms. All the results revealed the formation of pure, low crystalline and discrete granular like HAP nanoparticles of size around 25 nm with enhanced biological and antimicrobial activities. Hence the as-synthesized nanoparticles can act as a better bone regenerating material in the field of biomedicine. 
Entered by:
Kavitha Louis on 2020-09-02 
 
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